Type locality: Wimbledon, North Dakota, USA; holotype male in US National Museum.
The type species of Neopius is a junior subjective synonym of Opius rudis Wesmael, lectotype female in Brussels, designated by Koenig (1972), who noted that the large type series consisted of several apparent species. The synonymy was first noted by Fischer (1967: 959)
In the process of separating Euopius Fischer from Neopius Gahan, Fischer (1967) placed Neopius as a junior subjective synonym of Opius. Later, Fischer (1972: 88) placed the type species of Neopius in the Opius subgenus Xynobius, though he neglected to list Neopius in the synonymy under Xynobius. Wharton (2006) noted that rudis was quite different from the type species of Xynobius in many respects and should not be included in Xynobius, following similar statements by Quicke et al. (1997), who placed Neopius as a subgenus and therefore a synonym of Phaedrotoma. Li et al. (2013) list Neopius Gahan as a valid genus.
There is some confusion regarding Neopius. Fischer (1967: 959-960) apparently realized that most of the species that he previously included in Neopius Gahan were different from Gahan’s type species and he therefore described a new genus (Euopius) to accommodate them. There was never a Neopius Fischer, only a Neopius Gahan sensu Fischer (1965). Fischer (1977: 1) is unfortunately a bit confusing in this regard. Li et al. (2013) compound the confusion by listing Neopius Fischer, 1965 (with type species by original designation Neopius macrops Fischer) as a synonym of Phaedrotoma. However, Fischer (1965: 187) clearly attributes Neopius to Gahan and lists carinaticeps as the type species. Fischer (1965) only included descriptions of those species that he was newly describing (all of which he later transferred to Euopius), but does include carinaticeps in his key to the known species.